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Els for levels of hemoglobin concentration or imply corpuscular volume attenuate
BMC Healthcare Genetics 2012, 13:30 http://www.biomedcentral.com/1471-2350/13/Table 4 Association of 11 SNPs as well as the Genotype Score with mortality by race-ethnicity, Third National Overall health and Nutrition Examination Survey (NHANES III)Mortality at 13.5 years Race-ethnicity SNPs N with 0, 1, or two Risk Allele 0 1 two SNP per-risk alelle raise in mortality (OR) (95 CI) p-value1 mortality events Age and race standardized weighted mortality ( ) per 1000 person-years (95 CI) 12.8 (11.0?4.6) 11 SNP Genotype Score per-risk alelle raise in mortality (OR) (95 CI) 1.07 (0.99?.16) p-value143 Non-Hispanic White rs2022003 Nepicastat (hydrochloride) custom synthesis rs552976 Nepicastat (hydrochloride)Biological Activity rs1800562 rs1799884 rs4737009 rs6474359 rs16926246 rs10830956 rs282606 rs1046896 rs855791 1,226 1,192 1,204 1,207 1,183 1,174 1,206 1,173 1,183 1,205 1,183 52.8 9.9 0.1 69.2 57.7 0.1 two.5 49.three 74.four 47.four 33.two 39.1 41.five 8.0 27.six 35.1 six.eight 20.7 42.9 22.9 42.9 48.three eight.1 48.6 91.9 three.3 7.two 93.1 76.eight 7.9 two.7 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28499442 9.7 18.five 1.12 (0.81?.55) 0.93 (0.68?.27) 1.07 (0.45?.55) 0.98 (0.68?.40) 0.97 (0.65?.47) 0.91 (0.48?.69) 1.34 (0.88?.05) 1.14 (0.79?.65) 0.85 (0.58?.22) 1.11 (0.80?.54) 1.14 (0.81?.62) 0.48 0.68 0.88 0.90 0.91 0.76 0.17 0.48 0.37 0.52 0.45 100 Non-Hispanic Black rs2022003 rs552976 rs1800562 rs1799884 rs4737009 rs6474359 rs16926246 rs10830956 rs282606 rs1046896 rs855791 869 882 887 888 861 853 885 832 859 888 857 55.2 10.2 0.1 68.7 19.0 6.4 1.six 37.7 20.2 50.two 70.two 39.two 42.8 7.1 28.2 51.7 38.6 19.7 47.0 50.8 40.9 25.six five.six 47.0 92.eight 3.1 29.3 55.1 78.7 15.three 29.1 8.9 4.two 1.40 (0.97?.04) 0.96 (0.67?.39) two.81 (1.11?.13) 0.96 (0.65?.43) 1.11 (0.77?.59) 0.73 (0.51?.03) 1.13 (0.66?.92) 1.18 (0.84?.67) 0.93 (0.68?.27) 1.17 (0.85?.63) 0.93 (0.63?.38) 0.07 0.84 0.03 0.86 0.57 0.08 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26240184 0.66 0.34 0.0.19.4 (15.8?2.9)1.04(0.95?.14)0.Web page 7 of0.33 0.Table 4 Association of 11 SNPs plus the Genotype Score with mortality by race-ethnicity, Third National Overall health and Nutrition Examination Survey (NHANES III) (Continued)55 Mexican American rs2022003 rs552976 rs1800562 rs1799884 rs4737009 rs6474359 rs16926246 rs10830956 rs282606 rs1046896 rs855791 896 890 904 904 884 883 904 874 882 904 878 41.9 13.6 0.1 68.7 57.6 0.2 1.3 59.7 67.6 47.three 30.2 45.6 41.Els for levels of hemoglobin concentration or mean corpuscular volume attenuate SNP-HbA1c relationships, suggesting mediation of HbA1c varation by elements of erythrocyte biology [7].
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